Inappropriate use of aspirin for primary prevention

The Use of Aspirin in Primary Prevention of Cardiovascular Disease.

The use of aspirin to prevent future cardiovascular events in those with a prior history of cardiovascular disease is recommended by all relevant guidelines and is supported by a strong evidence base. However, there has been much publicity and debate resulting from recent reports questioning the benefits of aspirin use in those with no history of prior cardiovascular disease, including those wi...

Use and Misuse of Aspirin in Primary Cardiovascular Prevention

The use of low-dose aspirin in primary prevention of cardiovascular (CV) events in healthy or apparently healthy people is a widely debated topic. Many arguments indicate that "primary prevention" is only a conventional definition and that the transition from primary to secondary prevention represents a continuum of increasing levels of CV risk. Although there are no direct proofs of a differen...

Aspirin for primary prevention of cardiovascular disease

Cardiovascular disease (CVD) is a leading cause of mortality.1 For example, in 2000, it accounted directly for around 2 million deaths in the European Union.2 Worldwide, many people take aspirin daily in the belief that doing so helps to prevent CVD. This approach is established for the secondary prevention of recurrent vascular events. However, there has been some uncertainty about the place o...

Aspirin for Primary Prevention: A Challenging Decision

A spirin for primary prevention of cardiovascular disease (CVD) remains a challenging issue for clinicians, patients, and health policy makers. Even with the availability of multiple randomized trials and several high-quality systematic reviews and meta-analyses, significant debate remains about which patients, if any, should be offered aspirin for primary prevention. The main US guideline-issu...

Authors' reply on aspirin for primary prevention.